While BEN in DMN/ECN increases with age, it decreases with education years. Functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) are well-established tools for investigating the human motor system in-vivo. Based on rs-fMRI data, functional connectivity (FC) has been calculated using correlations between spatially distant regions within/across functional networks (Rogers, Morgan, Newton, & Gore, 2007. Our results unanimously highlighted two brain circuits: the default mode network (DMN) and executive control network (ECN) through their negative associations of BEN to general functionality, which is independent of age and sex. Without any task or external stimulus, rs-fMRI can capture the spontaneous brain activity that reflects the functional organization of the brain. To address this standing question and to test a novel hypothesis that resting BEN reflects a latent functional reserve through the link to general functionality, we mapped resting BEN of 862 young adults and comprehensively examined its associations to neurocognitions using data from the Human Connectome Project (HCP). Human Brain Mapping This article is protected by copyright. 22 Previous findings demonstrated that the BOLD-fMRI signals follow a power-law of 40 John Wiley & Sons, Inc. 21 The LRTCs implies the temporal memory of brain activity in long time scales. While BEN mapping results have shown sensitivity to neuromodulations or disease conditions, the underlying neuromechanisms especially the associations of BEN or LRTC to neurocognition still remain unclear. 20 temporal correlations (LRTCs) has been introduced in fMRI studies (He, et al., 2010). The long-range temporal coherence (LRTC) can be characterized by resting state fMRI (rsfMRI)-based brain entropy (BEN) mapping. The latent reserve if it exists may be reflected by the profound long-range fluctuations of resting brain activity. Here specialization was explored using fMRI by examining the degree to which brain networks preferentially interact with ipsilateral as opposed to contralateral networks. Using fMRI brain activation to identify cognitive states associated with perception of tools and dwellings.
J Wang, JA Conder, DN Blitzer, SV Shinkareva. Resting state brain activity consumes most of brain energy, likely creating and maintaining a reserve of general brain functionality. The human brain demonstrates functional specialization, including strong hemispheric asymmetries. Neural representation of abstract and concrete concepts: A metaanalysis of neuroimaging studies.